At Callisto BioMed, we specialize in advanced lipoprotein profiling that delivers unmatched assessment of cardiovascular risk. Unlike standard lipid panels, our tests analyze lipoprotein subfractions with high analytical precision—enabling earlier detection, more accurate results, and more personalized decisions.

HDL Subfraction Testing

Our HDL analysis separates high-density lipoprotein into five clinically distinct subfractions:
HDL2b, HDL2a, HDL3a, HDL3b, and HDL3c

• HDL2b is associated with atheroprotection and optimal reverse cholesterol transport.

• HDL3 subfractions (especially HDL3b and HDL3c) are linked to inflammation, metabolic syndrome, and increased cardiovascular risk.

Our test quantifies these patterns to help providers better evaluate the functionality of HDL—not just the total quantity.

LDL Subfraction Testing

We characterize LDL particles across the spectrum of density and size.
Most importantly, we detect and quantify small dense LDL (sdLDL)—the highly atherogenic form of LDL that standard panels often miss.

• sdLDL penetrates the arterial wall more easily and is more prone to oxidation, making it a critical risk marker even when LDL-C is "normal."

HDL + LDL Subfraction Testing (Dual Panel)

Callisto BioMed is the only provider offering combined HDL + LDL subfraction analysis in a single test.

This unique panel delivers a comprehensive lipoprotein risk profile, allowing for:

• Enhanced risk stratification

• More informed treatment decisions

• Streamlined ordering and reduced sample volume